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human normal lung epithelial beas 2b cells  (ATCC)
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Acidic microenvironment condition screening and LAMC2 expression validation. (A) Comparison of relative LAMC2 expression levels in different cell lines <t>(BEAS-2B,</t> HCC827, and A549), showing a significantly higher expression in HCC827 and A549 cells compared to BEAS-2B cells. (B) Changes in LAMC2 expression in HCC827 and A549 cells under different lactate (LA) concentrations (10, 20, and 30 mM), showing significant increases in LAMC2 expression at 20 and 30 mM concentrations. (C) Changes in LAMC2 expression over time (0, 6, 12, and 24 h) in HCC827 and A549 cells treated with 20 mM LA, showing a significant increase in expression with longer treatment times. (D) Changes in LAMC2 expression under different acidic environment conditions (high LA, hydrochloric-acid-induced acidosis, and control groups) in HCC827 and A549 cells, with a significantly higher expression in the high LA and hydrochloric-acid-induced acidosis groups. ** p < 0.01, *** p < 0.001, **** p < 0.0001.
Human Normal Lung Epithelial Beas 2b Cells, supplied by ATCC, used in various techniques. Bioz Stars score: 99/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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human normal lung epithelial cells beas 2b  (Procell Inc)
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Procell Inc human normal lung epithelial cells beas 2b
Acidic microenvironment condition screening and LAMC2 expression validation. (A) Comparison of relative LAMC2 expression levels in different cell lines <t>(BEAS-2B,</t> HCC827, and A549), showing a significantly higher expression in HCC827 and A549 cells compared to BEAS-2B cells. (B) Changes in LAMC2 expression in HCC827 and A549 cells under different lactate (LA) concentrations (10, 20, and 30 mM), showing significant increases in LAMC2 expression at 20 and 30 mM concentrations. (C) Changes in LAMC2 expression over time (0, 6, 12, and 24 h) in HCC827 and A549 cells treated with 20 mM LA, showing a significant increase in expression with longer treatment times. (D) Changes in LAMC2 expression under different acidic environment conditions (high LA, hydrochloric-acid-induced acidosis, and control groups) in HCC827 and A549 cells, with a significantly higher expression in the high LA and hydrochloric-acid-induced acidosis groups. ** p < 0.01, *** p < 0.001, **** p < 0.0001.
Human Normal Lung Epithelial Cells Beas 2b, supplied by Procell Inc, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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human normal lung epithelial cells beas 2b  (ATCC)
99
ATCC human normal lung epithelial cells beas 2b
Acidic microenvironment condition screening and LAMC2 expression validation. (A) Comparison of relative LAMC2 expression levels in different cell lines <t>(BEAS-2B,</t> HCC827, and A549), showing a significantly higher expression in HCC827 and A549 cells compared to BEAS-2B cells. (B) Changes in LAMC2 expression in HCC827 and A549 cells under different lactate (LA) concentrations (10, 20, and 30 mM), showing significant increases in LAMC2 expression at 20 and 30 mM concentrations. (C) Changes in LAMC2 expression over time (0, 6, 12, and 24 h) in HCC827 and A549 cells treated with 20 mM LA, showing a significant increase in expression with longer treatment times. (D) Changes in LAMC2 expression under different acidic environment conditions (high LA, hydrochloric-acid-induced acidosis, and control groups) in HCC827 and A549 cells, with a significantly higher expression in the high LA and hydrochloric-acid-induced acidosis groups. ** p < 0.01, *** p < 0.001, **** p < 0.0001.
Human Normal Lung Epithelial Cells Beas 2b, supplied by ATCC, used in various techniques. Bioz Stars score: 99/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/human normal lung epithelial cells beas 2b/product/ATCC
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beas 2b human normal lung epithelial cells  (Procell Inc)
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Procell Inc beas 2b human normal lung epithelial cells
Acidic microenvironment condition screening and LAMC2 expression validation. (A) Comparison of relative LAMC2 expression levels in different cell lines <t>(BEAS-2B,</t> HCC827, and A549), showing a significantly higher expression in HCC827 and A549 cells compared to BEAS-2B cells. (B) Changes in LAMC2 expression in HCC827 and A549 cells under different lactate (LA) concentrations (10, 20, and 30 mM), showing significant increases in LAMC2 expression at 20 and 30 mM concentrations. (C) Changes in LAMC2 expression over time (0, 6, 12, and 24 h) in HCC827 and A549 cells treated with 20 mM LA, showing a significant increase in expression with longer treatment times. (D) Changes in LAMC2 expression under different acidic environment conditions (high LA, hydrochloric-acid-induced acidosis, and control groups) in HCC827 and A549 cells, with a significantly higher expression in the high LA and hydrochloric-acid-induced acidosis groups. ** p < 0.01, *** p < 0.001, **** p < 0.0001.
Beas 2b Human Normal Lung Epithelial Cells, supplied by Procell Inc, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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human normal lung epithelial cells  (ATCC)
99
ATCC human normal lung epithelial cells
Acidic microenvironment condition screening and LAMC2 expression validation. (A) Comparison of relative LAMC2 expression levels in different cell lines <t>(BEAS-2B,</t> HCC827, and A549), showing a significantly higher expression in HCC827 and A549 cells compared to BEAS-2B cells. (B) Changes in LAMC2 expression in HCC827 and A549 cells under different lactate (LA) concentrations (10, 20, and 30 mM), showing significant increases in LAMC2 expression at 20 and 30 mM concentrations. (C) Changes in LAMC2 expression over time (0, 6, 12, and 24 h) in HCC827 and A549 cells treated with 20 mM LA, showing a significant increase in expression with longer treatment times. (D) Changes in LAMC2 expression under different acidic environment conditions (high LA, hydrochloric-acid-induced acidosis, and control groups) in HCC827 and A549 cells, with a significantly higher expression in the high LA and hydrochloric-acid-induced acidosis groups. ** p < 0.01, *** p < 0.001, **** p < 0.0001.
Human Normal Lung Epithelial Cells, supplied by ATCC, used in various techniques. Bioz Stars score: 99/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/human normal lung epithelial cells/product/ATCC
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human normal lung epithelial cells - by Bioz Stars, 2026-05
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human normal lung epithelial cell line beas 2b  (Procell Inc)
86
Procell Inc human normal lung epithelial cell line beas 2b
Acidic microenvironment condition screening and LAMC2 expression validation. (A) Comparison of relative LAMC2 expression levels in different cell lines <t>(BEAS-2B,</t> HCC827, and A549), showing a significantly higher expression in HCC827 and A549 cells compared to BEAS-2B cells. (B) Changes in LAMC2 expression in HCC827 and A549 cells under different lactate (LA) concentrations (10, 20, and 30 mM), showing significant increases in LAMC2 expression at 20 and 30 mM concentrations. (C) Changes in LAMC2 expression over time (0, 6, 12, and 24 h) in HCC827 and A549 cells treated with 20 mM LA, showing a significant increase in expression with longer treatment times. (D) Changes in LAMC2 expression under different acidic environment conditions (high LA, hydrochloric-acid-induced acidosis, and control groups) in HCC827 and A549 cells, with a significantly higher expression in the high LA and hydrochloric-acid-induced acidosis groups. ** p < 0.01, *** p < 0.001, **** p < 0.0001.
Human Normal Lung Epithelial Cell Line Beas 2b, supplied by Procell Inc, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/human normal lung epithelial cell line beas 2b/product/Procell Inc
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human normal lung epithelial cell line beas 2b - by Bioz Stars, 2026-05
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normal human lung epithelial cells beas2b  (ATCC)
99
ATCC normal human lung epithelial cells beas2b
Acidic microenvironment condition screening and LAMC2 expression validation. (A) Comparison of relative LAMC2 expression levels in different cell lines <t>(BEAS-2B,</t> HCC827, and A549), showing a significantly higher expression in HCC827 and A549 cells compared to BEAS-2B cells. (B) Changes in LAMC2 expression in HCC827 and A549 cells under different lactate (LA) concentrations (10, 20, and 30 mM), showing significant increases in LAMC2 expression at 20 and 30 mM concentrations. (C) Changes in LAMC2 expression over time (0, 6, 12, and 24 h) in HCC827 and A549 cells treated with 20 mM LA, showing a significant increase in expression with longer treatment times. (D) Changes in LAMC2 expression under different acidic environment conditions (high LA, hydrochloric-acid-induced acidosis, and control groups) in HCC827 and A549 cells, with a significantly higher expression in the high LA and hydrochloric-acid-induced acidosis groups. ** p < 0.01, *** p < 0.001, **** p < 0.0001.
Normal Human Lung Epithelial Cells Beas2b, supplied by ATCC, used in various techniques. Bioz Stars score: 99/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/normal human lung epithelial cells beas2b/product/ATCC
Average 99 stars, based on 1 article reviews
normal human lung epithelial cells beas2b - by Bioz Stars, 2026-05
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Acidic microenvironment condition screening and LAMC2 expression validation. (A) Comparison of relative LAMC2 expression levels in different cell lines (BEAS-2B, HCC827, and A549), showing a significantly higher expression in HCC827 and A549 cells compared to BEAS-2B cells. (B) Changes in LAMC2 expression in HCC827 and A549 cells under different lactate (LA) concentrations (10, 20, and 30 mM), showing significant increases in LAMC2 expression at 20 and 30 mM concentrations. (C) Changes in LAMC2 expression over time (0, 6, 12, and 24 h) in HCC827 and A549 cells treated with 20 mM LA, showing a significant increase in expression with longer treatment times. (D) Changes in LAMC2 expression under different acidic environment conditions (high LA, hydrochloric-acid-induced acidosis, and control groups) in HCC827 and A549 cells, with a significantly higher expression in the high LA and hydrochloric-acid-induced acidosis groups. ** p < 0.01, *** p < 0.001, **** p < 0.0001.

Journal: Frontiers in Oncology

Article Title: Acidic microenvironment-induced LAMC2 expression promotes proliferation, migration, and pathway regulation in non-small cell lung cancer cells

doi: 10.3389/fonc.2026.1747868

Figure Lengend Snippet: Acidic microenvironment condition screening and LAMC2 expression validation. (A) Comparison of relative LAMC2 expression levels in different cell lines (BEAS-2B, HCC827, and A549), showing a significantly higher expression in HCC827 and A549 cells compared to BEAS-2B cells. (B) Changes in LAMC2 expression in HCC827 and A549 cells under different lactate (LA) concentrations (10, 20, and 30 mM), showing significant increases in LAMC2 expression at 20 and 30 mM concentrations. (C) Changes in LAMC2 expression over time (0, 6, 12, and 24 h) in HCC827 and A549 cells treated with 20 mM LA, showing a significant increase in expression with longer treatment times. (D) Changes in LAMC2 expression under different acidic environment conditions (high LA, hydrochloric-acid-induced acidosis, and control groups) in HCC827 and A549 cells, with a significantly higher expression in the high LA and hydrochloric-acid-induced acidosis groups. ** p < 0.01, *** p < 0.001, **** p < 0.0001.

Article Snippet: Human normal lung epithelial BEAS-2B cells (ATCC ® CRL-9609TM) and lung cancer cell lines A549 (Procell, CL-0016, lung adenocarcinoma) and HCC827 (Procell, CL-0094, lung adenocarcinoma) were obtained from the indicated suppliers.

Techniques: Expressing, Biomarker Discovery, Comparison, Control